Yeah, they can! In cisgender men and people assigned male at birth, anal sex can stimulate the prostate and lead to an orgasm. Prostate orgasms are intense enough to send waves of orgasmic pleasure from head to toe. For cisgender women and people assigned female at birth, anal sex can hit two hot spots: the G-spot and A-spot. Both are located along the vaginal wall but can be indirectly stimulated during anal. Like the prostate, these spots have the potential to produce full-body orgasms. Taboo or forbidden sex is a common sexual fantasy.